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Ion chromatography (IC) is a specialized form of high-performance liquid chromatography (HPLC) designed for the separation and detection of ionic species in solution, including inorganic and organic anions, cations, and polar molecules. Its main advantages include efficient ion separation, high-sensitivity detection, simultaneous multi-component analysis, automation, and high throughput. IC operates based on the principle of ion exchange, utilizing the interactions between the stationary phase (ion-exchange resin) and the mobile phase to achieve efficient separation of different ions. Additionally, it can distinguish between different oxidation states of the same element.
The basic components of an ion chromatography system include:
Chromatographic column: Typically composed of ion-exchange resins or other specialized materials used for separating different ionic compounds.
Sample solution: The sample to be analyzed is usually dissolved in water or another solvent.
Detector: Used to detect the presence and concentration of ionic compounds.
The separation process in ion chromatography relies on the interaction characteristics of ions in the solution with the chromatographic packing material in the column. These interactions include ion exchange, affinity adsorption, exclusion effects, and more. By adjusting the column packing and operating conditions such as flow rate, temperature, and gradients, selective separation of different ions can be achieved.
In the detection of inorganic ions:
In the detection of organic ions:
1. Aqueous solution
2. Testable ion species include: Br⁻, F⁻, Cl⁻, SO₄²⁻, NO₃⁻, NO₂⁻, PO₄³⁻, formate, acetate, propionate, butyrate, valerate, NH₄⁺, Li⁺, Na⁺, K⁺, Mg²⁺, and Ca²⁺.
3. For special samples or specific ion content testing requirements, please consult your account manager.
Ion chromatography is commonly used for the analysis of ions in water samples, including cations (e.g., sodium, potassium, ammonium ions) and anions (e.g., chloride ions, nitrate ions, sulfate ions).
Ion chromatography (IC) is a chemical analysis technique used for the separation and analysis of ionic compounds in solution. It is an efficient and highly sensitive analytical method widely applied in environmental monitoring, food analysis, biochemistry, pharmaceuticals, and other fields.